Moreover, the UBE2C and hsa-miR-139-5p analysis based on in-house RNA-seq showed that the average expression value of UBE2C mRNA was significantly higher in ESCC (5.8418 ± 0.56367) than in control (2.2041 ± 1.4291, p < 0.0001) tissues. This evidence concerns the gene UBE2C and esophageal squamous cell carcinoma.