NLRP3 and non-small cell lung carcinoma: Interestingly, miR-556-5p is reported to regulate NLRP3-mediated cell pyroptosis in OVA-induced AR mice models [43], suggesting that NLRP3 is the downstream target of miR-556-5p, which were supported by our experiments that miR-556-5p targeted the 3ʹUTR of NLRP3 mRNA for its inhibition in NSCLC, and the expression levels of miR-556-5p and NLRP3 mRNA showed negative correlations in the clinical NSCLC tissues.