NLRP3 and non-small cell lung carcinoma: Then, the Real-Time qPCR and Western Blot analysis were performed, and the results showed that NLRP3 was significantly downregulated in the CR-NSCLC cells, in contrast with the CS-NSCLC cells (Figure 4(d,e)), which were supported by the clinical results that NLRP3 tended to be downregulated in the CR-NSCLC tissues (Figure 4(f)), and the expression levels of miR-556-5p and NLRP3 mRNA showed negative correlations in the NSCLC tissues (Figure 4(g)).