Recent studies demonstrated that lung ADC cells showed IFNG hypo-responsiveness even though there were no differences in the expression of IFNGR1 and IFNGR2.38 Our findings of overexpression of histone deacetylase HDAC11 correspond to those of a recent study which reports that high HDAC11 levels in human lung tumor tissues correlate with poor prognosis. This evidence concerns the gene HDAC11 and medical procedure.