When patients were divided according to optimal cut-off values, the relapse-free survival curves in the subgroups differed significantly between the values above and below the optimal values of PET parameters for each threshold, especially for 40% of tumor SUVmax for TLG (TLG 40%), SUVmax of 3.5 for MTV (MTV 3.5), and TLR of 2 for MTV (MTV-TLR2) (Figs. 3 and 4). Here, TLR2 is linked to neoplasm.