As a result, We found high ACTB expression was correlated with poor overall survival (OS) for GBM (P = 0.03), HNSC (P = 0.0054), KIRC (P = 0.0065), LGG (P = 0.00047), LIHC (P = 0.0074), LUAD (P = 0.0043), MESO (P = 6.1e-06), SKCM (P = 0.046) and UVM (P = 0.0026) from TCGA datasets (Figure 3(a)). The gene discussed is ACTB; the disease is glioblastoma.