The two hub genes SCN10A (grey60 module) and SCN11A (cyan module) peaked around D16, and SCN8A a voltage‐gated sodium channel which is essential for neuron function in mammalian neuronal tissues and in the pathogenesis of neuropathic pain[53, 54, 55] peaked already at D9 at the transition from pluripotency to neuronal differentiation (Figure 1F, Figure 6B). This evidence concerns the gene SCN8A and Pain.