This is particularly relevant when considering recent transcriptome‐wide association studies that show dysregulation in the expression of several GPCRs including MCHR1, in individuals with schizophrenia87 and the implication of single nucleotide polymorphisms in the PDLIM5 gene and susceptibility to neurological conditions, including schizophrenia.77, 78, 79. The gene discussed is PDLIM5; the disease is schizophrenia.