METTL3 and cancer: According to the above Materials and Methods, immunohistochemistry scoring was performed based on the scoring standard, and the results showed that the level of PP2Acα in GC tissue was significantly lower than that in normal gastric mucosal tissue adjacent to the cancer (P < 0.001; Figure 1(a)), while the level of METTL3 was significantly increased in GC tissue (P < 0.0001; Figure 1(b)).