An alternative strategy proposed by us10 envisaged a focused secretion of lymphokines like IL2 by helper T-cells directly onto the effector lymphocytes (anti-tumour T-cells in our case) bringing in a high magnitude of selective in vivo amplification of desired T-cells minimising the chances of non-specific amplification of harmful lymphocytes like the anti-idiotypic or the suppressor lymphocytes and phagocytes. Here, IL2 is linked to neoplasm.