IL10 and parasitic infectious disease: Host genetic factors, such as genetic polymorphisms altering expression of cytokines key in the Th1/Th2 differential responses, have been recognised as key influencers in parasitic infections, prognosis, morbidity, treatment outcomes and vaccine development.7,8 Severity of symptoms has been associated with cytokines that influence the granulomatous response, namely, interleukin-10 (IL-10) and tumour necrosis factor alpha (TNF-α).