Jang et al. found that lycopene inhibited Helicobacter pylori-induced human gastric adenocarcinoma cell line AGS cells increases in ROS, apoptosis, cell cycle distribution changes, double-strand DNA breaks, ataxia-telangiectasia-mutated (ATM), and ATM-Rad3-related DNA damage response (14). The gene discussed is ATM; the disease is gastric adenocarcinoma.