Upregulation of S100A8 and S100A9 occurs in various human cancer types and may participate in tumor growth, metastasis, angiogenesis and immune evasion (Ichikawa et al., 2011; Grebhardt et al., 2014; Goh et al., 2017; Mondet et al., 2021). Here, S100A9 is linked to neoplasm.