MTOR and anemia (phenotype): In terms of erythroid cell commitment, mTOR inhibition by rapamycin significantly improved erythroid cell maturation and anaemia in a β-thalassemia mouse model (Zhang et al., 2014), whereas suppression of mTOR signalling markedly reduced the proportion of erythroid progenitor cells in a population of wild-type bone marrow cells (Liu et al., 2020).