Some lncRNAs, such as UCA1 (Li Z.G. et al., 2020), FOXD2-AS1 (Zhao et al., 2020), RP11-84E24.3 (Chang et al., 2021), CTBP1-AS2 (Li Y. et al., 2020), and LINC00525 (Wan et al., 2020) can promote EMT in gliomas while other lncRNAs, such as CASC2 (Wang et al., 2020) and GAS5 (Zhu X.P. et al., 2020) can inhibit EMT in gliomas. The gene discussed is UCA1; the disease is central nervous system cancer.