Some lncRNAs, such as UCA1 (Li Z.G. et al., 2020), FOXD2-AS1 (Zhao et al., 2020), RP11-84E24.3 (Chang et al., 2021), CTBP1-AS2 (Li Y. et al., 2020), and LINC00525 (Wan et al., 2020) can promote EMT in gliomas while other lncRNAs, such as CASC2 (Wang et al., 2020) and GAS5 (Zhu X.P. et al., 2020) can inhibit EMT in gliomas. This evidence concerns the gene CASC2 and central nervous system cancer.