Primary NK cells from umbilical cord blood (UCB) could overcome this cavity and stimulation with IL-2 and IL-15 or UCB-derived NK cells expressing the TGF-β- dominant-negative receptor II, consuming TGF-β of the tumor microenvironment of glioblastoma is of interest (Burster et al., 2021). The gene discussed is TGFB1; the disease is neoplasm.