Additionally, the anti-apoptotic Bcl-2 family member myeloid cell leukemia factor-1 (Mcl-1), which interferes in early cascade events by suppressing cytochrome c release from mitochondria, is highly expressed in human glioblastoma (Michels et al., 2005; Karpel-Massler et al., 2017). This evidence concerns the gene MCL1 and glioblastoma.