human leukocyte antigen, HLA) class I polypeptide-related sequence B (MICB) has been reported in normal appearing white matter (NAWM) (Huynh et al., 2014) and CD4+T cells (Graves et al., 2014) in MS patient; also, the MICB activates destruction of NK and CD8+T cells in MS (Meresse et al., 2006). This evidence concerns the gene CD4 and myeloid sarcoma.