FLT3 and acute myeloid leukemia: GATA2, CSF3R and other tyrosine kinase genes (KIT, JAK3 and FLT3-ITD), WT1 and genes involved in chromatin/DNA modification, cohesin complex, and splicing were identified as hotspots in recent studies to decipher prognostic stratification in biCEBPA mutated AML (6, 8–12).