Moreover, qRT-PCR results manifested that overexpressing YY1 facilitated the MIR31HG expression in CRC cells and HUVECs (P<0.05, Figure 5I), while knockdown of YY1 significantly reduced the expression of MIR31HG (P<0.05, Figure 5J). The gene discussed is MIR31HG; the disease is colorectal carcinoma.