To further evaluate the suppressive effect of ACAT1 expression on NPC tumor cell growth, we compared the tumorigenesis of ACAT1-5-8F and ACAT1-HONE1 to that of the respective pCMV6-Entry control clones of 5-8F and HONE1 in vivo. This evidence concerns the gene ACAT1 and nasopharyngeal carcinoma.