CMIP contributes to several biological pathways and is involved in various diseases such as glioma, gastric cancer, kidney disease, and dyslipidemia (Li et al., 2019; Mo et al., 2018; Wang & Wu, 2017; Zhang et al., 2017), as well as major depressive disorder, syndromic autism spectrum disorders, and specific language impairments (Eicher & Gruen, 2015; Gedik, 2017; Luo et al., 2017; Wang et al., 2015). Here, CMIP is linked to major depressive disorder.