In addition, PIK3R2 was also significantly upregulated in liver cancer patients (p < 0.001), and the OS time and disease-free survival (DFS) time of patients with high expression of PIK3R2 were also significantly shorter than those with low expression of PIK3R2 (OS: HR = 2, p = 0.0053; DFS: HR = 1.9, p = 0.005). The gene discussed is PIK3R2; the disease is liver cancer.