SARS-CoV-2-related CS is confirmed by several studies showing increased level of proinflammatory factors, such as IL-1, IL-6, IL-10, IFNγ, granulocyte colony stimulating factor (G-CSF), monocyte chemoattractant protein (MCP1), macrophage inflammatory protein 1 alpha (MIP1A), platelet-derived growth factor (PDGF), TNFα, and vascular endothelial growth factor (VEGF) [46, 91]. This evidence concerns the gene VEGFA and Cowden syndrome 1.