NLRP3 and bone cancer: As depicted in Figures 5(a)–5(c), western blotting results showed that compared with the sham group, the expression of p-NF-κB and NLRP3 in the spinal cord of BCP rats increased significantly with bone cancer progression (∗∗∗p < 0.001 vs. the sham group; n = 4, one-way ANOVA, Figures 5(a)–5(c)).