GLRA3 and Stroke: Thirdly, functional analysis results indicated that more downregulated DEGs in EA-pretreated stroke rats participated in the 26 common function categories, and these downregulated DEGs encoding proteins were also involved in the neuro-excitotoxicity-related processes such as ion channel and transport (ligand-gated ion channel, chloride channel, voltage-gated channel, and symport), postsynaptic cell membrane, and synapse.