CTLA4 and neoplasm: The general linear model analysis demonstrated that staining for T cells (CD3+) and malignant cells PD-L1 were associated with the overall stage (P = 0.019), whereas TILs LAG-3 and CTLA-4+, NK cells (CD57+), and macrophages (CD68+) were associated with the presence of T2 tumor stage (P = 0.04, P = 0.01, P = 0.01, and P = 0.003; respectively).