LAG3 and neoplasm: Overall, the amount of cytotoxic T cells CD8+, TILs CTLA-4+, and macrophages CD68+ was prominent in the tumor tissue than in the normal tissue and intermediated portion of the tumor, as were the amount of LAG-3, CTLA-4+, macrophages CD68+, and NK cells CD57+, while malignant PD-L1 cells were moderately distributed.