Moreover, we found that HLA-DRB1 tended to be higher expressed in HLA-DRB1*04 and *07 alleles compared to HLA-DRB1*03 and *15 alleles in both healthy individuals from the GTEx project and RA patients from EIRA/RECOMBINE study. The gene discussed is HLA-DRB1; the disease is rheumatoid arthritis.