Among pSS patients with distinct MSG lesion severity, those with severe infiltrates were found to express significantly higher CXCL13 serum levels compared to those with mild lesions (105.7 pg/ml vs 34.63 pg/ml, respectively, p=0.012), whereas saliva levels did not differ significantly among the three pSS subgroups. Here, CXCL13 is linked to peeling skin syndrome.