Gene expression analysis between the late sepsis patients with bacteremia (n=2) versus fungemia (n=2) revealed differential expression of 25 genes in CD4+ T-lymphocytes, 44 genes in CD8+ T-lymphocytes, 93 genes in activated CD4+ T-lymphocytes, 368 genes in activated CD8+ T-lymphocytes, 24 genes in Tregs, 9 genes in NK T cells, 249 genes in NK cells, 16 genes in B-cells, and ten genes in pDCs (adjusted p-value< 0.01). This evidence concerns the gene CD4 and Sepsis.