CD4 and Sepsis: In the analysis of healthy controls (n=5) with all sepsis patients day 14-21 (n=4), scRNA-seq revealed differential expression of 11 genes in CD4+, 30 genes in CD8+, 26 genes in activated CD4+, 50 genes in activated CD8+, and 32 genes in regulatory T (Tregs) lymphocytes (adjusted p-value < 0.01; Supplementary Data Sheet 2 and Supplementary Table 2).