Younger SLE patients (36 vs 30 years old; p = 0.042), prednisolone intake (56.5% vs 88.9%; p = 0.009), and higher proportion of IL-23R+ Th cells (89.10% vs 92.40%; p = 0.017) were significantly associated with higher SLEDAI-2K scores (Table 2). Here, IL23R is linked to systemic lupus erythematosus.