Moreover, the proportions of IL-17RA+ (39.45% vs 23.65%; p = 1.12 x 10-4) and IL-23R+ (90.95% vs 33.25%; p = 1.98 x 10-29) Th cells were significantly higher in SLE patients compared with the healthy controls (Figure 2). This evidence concerns the gene IL23R and systemic lupus erythematosus.