One of the androgen pathways in COVID-19 infection is the transmembrane protease, serine 2 (TMPRSS2) gene that is expressed mainly in the adult prostate (56), and in metastatic prostate cancers; it is also found in tissues like lung, kidney, pancreas, colon, small intestine, and liver (56). This evidence concerns the gene TMPRSS2 and metastatic prostate carcinoma.