Among them, CTLA4 rs5742909 C>T allele was positively correlated with serum total IgE of EA patients (P =0.036), GSTM1 rs412302 G>A allele was positively correlated with blood eosinophil count of EA patients (P =0.047), and LTC4S rs3776944 G>A allele was negatively correlated with blood eosinophil percentage of EA patients (P =0.001). This evidence concerns the gene GSTM1 and Esophageal atresia.