The results of a case control study in Chilean population showed that the polymorphisms in the proteins of the RAS/RAF/MEK/ERK pathways, such as rs3729931 (RAF1), rs45604736 (HRAS), rs2283792, and rs9610417 (MAPK1), are associated with gastric cancer (Gonzalez-Hormazabal et al., 2019). Here, RAF1 is linked to gastric cancer.