We identified several SNPs in DHTKD1 that were highly significantly associated with cardiometabolic traits, including Type 2 Diabetes (top SNP rs11257655, p=2.4x10-61), glucose (top SNP rs11257655, p=5.x10-18), HbA1C (top SNP rs12221133, p=3.0x10-12) and Coronary Artery Disease (top SNP rs7068966, p=1.9x10-11). Here, DHTKD1 is linked to type 2 diabetes mellitus.