However, in other solid tumors, including glioblastoma, prostate, and breast cancer, the same miRNAs target important tumor suppressors - as Phosphatase and tensin homolog (PTEN), p27, p57 and TIMP metallopeptidase inhibitor 3 (TIMP3) - and function as oncogenic miRNAs (27–29). This evidence concerns the gene TIMP3 and breast carcinoma.