Rooryck C et al. (Rooryck et al., 2015) clearly associated heterozygous mutations on the TRDN gene (c.613C > T/p.Gln205 * and c.22 + 29 A> G) with the development of CPVT by studying a group of CPVT families. This evidence concerns the gene TRDN and catecholaminergic polymorphic ventricular tachycardia.