TNF and colitis: Moreover, the acute colitis produced a strong induction of mRNA expression levels of TNF-α, IL-1β, IL-6 and CXCL10, ranging from 233.5 ± 24.0% for IL6 to 663.5 ± 195.8% for TNF-α, in WTDSS mice compared to control group (Figures 10B–E; p <0.05).