MAPT and Schnyder corneal dystrophy: It is worth noting that pathologic tau and Aβ accumulation in the cholinergic nucleus basalis emerged early in AD (Arendt et al., 1988; Mesulam et al., 2004), and volume reductions in the basal forebrain were observed in patients with AD (Kilimann et al., 2014) and individuals with SCD (Scheef et al., 2019).