OPRM1 and ischemic stroke: As predicted, the relative expression level of GPR17 in the ischemic stroke group was significantly lower than that in the normal group (p < 0.01), whereas the relative expression of LPAR3 (p < 0.05), ADORA1 (p < 0.05), and OPRM1 (p < 0.01) in the ischemic stroke group was significantly higher than that in the normal group (Figure 8).