For example, CP-AMPAR increase in the amygdala was related to anxiety (Yi et al., 2017); in the lateral habenula it was linked to depression (Zhang et al., 2019); in hippocampus and cortices, it was implicated in seizures (Lippman-Bell et al., 2016), ischemia (Dias et al., 2013), AD (Whitehead et al., 2017), and schizophrenia (Umino et al., 2018); in the dorsal horn neurons, it was involved in chronic pain (Kopach et al., 2011), whereas, in the dorsal and ventral striatum, the CP-AMPAR increase was associated with HD (Mandal et al., 2011) and drug addiction (Ma et al., 2014), respectively. The gene discussed is CP; the disease is depressive disorder.