Whereas some data suggests a role of FAS in the context of endothelial cell proliferation and angiogenesis specifically under neoplastic conditions (Browne et al., 2006; Zaytseva et al., 2014; Bastos et al., 2017; Singh et al., 2017; Bruning et al., 2018), such aspects have not been addressed in endothelial cells exposed to an in vitro or in vivo stroke model. The gene discussed is FAS; the disease is Stroke.