The selective vulnerability of Reelin-positive hilar neurons has been described before in rodent epilepsy models (Gong et al., 2007; Orcinha et al., 2016) and in vitro in OHSC following KA exposure (Tinnes et al., 2011; Chai et al., 2014; Orcinha et al., 2016), but nobody performed such a detailed time course analysis showing death of hilar Reelin-positive cells already within 45 min after KA treatment. Here, RELN is linked to epilepsy.