Several genes known to cause CMT have been associated with dysfunctional endocytic processes, namely MTMR2,13,5, SH3TC2, FGD4, DNM2 (relating to the subtypes CMT4B, CMT4C,CMT4H, and DI-CMTB, respectively), which will be discussed below. Here, FGD4 is linked to Charcot-Marie-Tooth disease.