RAB7A and Charcot-Marie-Tooth disease type 1A: Abnormalities in lysosomal degradation have been reported for mutations in PMP22, LITAF, RAB7, DYNC1H1, LRSAM1, MTMR2,13,5, NDRG1, and FIG4 causing CMT1A, 1C, 2B, 2O, 2P, 4B, 4D, and 4J, respectively.