RAB27A and Griscelli syndrome type 2: Mutations of the Rab27a gene cause Griscelli syndrome type 2 manifesting in partial albinism due to insufficient melanosome transfer from skin melanocytes to keratinocytes and fatal hemophagocytic disorder due to defective lytic granule exocytosis in cytotoxic T lymphocytes (Ménasche et al., 2000).