In summary, 19 out of 20 regulators were differentially expressed, among which, 10 were up-regulated (EIF3A, HNRNPA2B1, YTHDC2, ZC3H13, ALKBH5, RBM15, METTL5, YTHDF1, RBM15B, YTHDF2) and 9 were down-regulated (METTL3, FTO, FMR1, YTHDC1, HNRNPC, WTAP, YTHDF3, IGF2BP2, KIAA1429) in DLBCL. The gene discussed is YTHDF1; the disease is diffuse large B-cell lymphoma.