Moreover, a significant increase in TAR level 2 (%, 10.1 ± 7.3 vs 16.7 ± 12.9, P < 0.001), mean glucose values (mg/dL, 160.2 ± 26.5 vs 175.5 ± 32.6, P = 0.001) and SD (mg/dL, 59.2 ± 13.1 vs 68.6 ± 17.7, P = 0.001) were found in the COVID-19 group at Time 2, without significant changes of total insulin doses, which slightly increased only during Time 2. This evidence concerns the gene INS and COVID-19.