Silencing tumor suppressor CEBPA via promoter hypermethylation has been reported in a number of human cancers.35,36 To explore whether the expression of CEBPA is suppressed by LMP1-mediated hypermethylation, we treated CNE1-TetOn-Vector and CNE1-TetOn-LMP1 cells with five dose series of the DNA-demethylating agent 5-aza-2′-deoxycytidine (Decitabine, DAC). This evidence concerns the gene CEBPA and cancer.