Given that SHH signaling was significantly suppressed in Rack1‐deficient GNPs,24 and deletion of Rack1 in SHH‐MB could significantly suppress the proliferation of tumor cells (Figure 2), therefore, we asked whether the absence of Rack1 in MB tumor cells could also induce the inactivation of SHH signaling. The gene discussed is SHH; the disease is neoplasm.