Ten of these 19 genes were expressed in oligodendrocytes, astrocytes, and/or OPCs and four of these genes including HSPA2, LPAR1, DOCK1, and PHLPP1 were significantly (FDR adjusted p < 0.05) differentially expressed between AD and control oligodendrocytes (Fig. 2c, Supplementary Fig. 9 and Supplementary Table 12). The gene discussed is PHLPP1; the disease is Alzheimer disease.