TF and central nervous system cancer: Liu and collaborators engineered a nano-vector composed by GO (lateral dimensions of 100–400 nm, complexed with PEG to improve its solubility) linked to transferrin (Tf), a glycoprotein that binds specific receptors overexpressed at the surface of glioma cells.64 Then, the anticancer drug doxorubicin was loaded to the GO complex (Tf-PEG-GO-doxorubicin) and tested in vitro and in vivo.64 First, in vitro tests detected that Tf-PEG-GO-doxorubicin was uptaken by C6 glioma cells at a faster rate when compared to unconjugated doxorubicin or GO-doxorubicin.