And the protein expressions of Bim and Bax increased in MDSCs from Dectin3−/− lupus mice compared with WT lupus mice; however, the expression of Bcl2 in MDSCs of Dectin3−/− mice with lupus was lower than that in WT mice with lupus (Fig. 3F). The gene discussed is BCL2L11; the disease is systemic lupus erythematosus.